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|Product Name:||Clenbuterol||Other Name:||Clebopride Malate|
|Product Production Standard:||USP36, American Pharmacopoeia, 99% Pure||Storage Conditions::||2-8 ° C（Or Put It In A Place Away From The Sun）|
|CAS Number:||37148-27-9||Molecular Formula:||C12H18Cl2N2O|
|Molecular Weight:||277.19000||Accurate Quality:||276.08000|
CAS 37148-27-9 Clenbuterol,
CAS 37148-27-9 Clebopride Malate,
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English name: Clenbuterol
English alias: clebopride malate
CAS Number: 37148-27-9 
Molecular formula: C12H18Cl2N2O
Molecular weight: 277.19000
Accurate quality: 276.08000
Physical and chemical properties
Appearance and properties: white crystalline solid
Density: 1.25 g/cm 3
Boiling point: 404.9ºC at 760 mmHg
Flash point: 198.7ºC
Storage conditions: the warehouse is low-temperature, ventilated, dry, and stored separately from food materials 
Overview of basic drug-related information
Chinese name: Clenbuterol
English name: Clenbuterol
Aliases: Dicloretin; Dicloretin; Diclofenac; Kechuanlai; Diclofenac; Diclofenac; Diclofenac; Dicloretin; Dicloretin; Salt ammonia diclosan Ann; Spiropent [2-3]
Respiratory system drugs> Asthma drugs> Airway dilation drugs 
Its hydrochloride is often used as a white or almost white crystalline powder; it is odorless and has a slightly bitter taste. It is soluble in water and ethanol, slightly soluble in chloroform or acetone, and insoluble in ether. The melting point is 172-176°C (decomposition). 
1. Tablets: 20μg, 40μg per tablet;
2. Film: 60μg, 120μg;
3. Aerosol: 1.96mg of clenbuterol; 
Clenbuterol is a potent β2 receptor agonist. It is characterized by a small effective dose and a long duration of action, and its bronchodilatory effect is 100 times that of salbutamol. Asthma patients take oral clenbuterol 30μg each time, 3 times a day, compared with oral terbutaline 5mg each time, 3 times a day. They have similar effects on increasing FEV1 and maximum expiratory flow rate (FEF) and reducing airway resistance. It can be seen that the anti-asthmatic effect of oral clenbuterol is 170 times stronger than terbutaline. 
Oral absorption is fast and complete, and it takes 15 minutes to take effect. The time for plasma drug concentration to reach peak is 2 to 3 hours, and the effect lasts for 6 to 8 hours. The drug distribution conforms to the two-chamber open model with peripheral chambers. The elimination from plasma can be divided into two phases. The half-life of plasma distribution is 1h, and the half-life of plasma metabolism is 34h. It is mainly excreted through the kidneys, and 87% is excreted after 168h. Dosing interval of 12h is sufficient to maintain blood concentration. Five metabolites have been found in the human body. The aerosol takes effect 5 to 10 minutes after inhalation, and the effect is maintained for 2 to 4 hours. After rectal administration (suppository), it takes effect 10 to 30 minutes and lasts for 8 to 24 hours. [2-3]
Used for bronchospasm caused by respiratory diseases such as bronchial asthma, asthma-like bronchitis, emphysema. [2-3]
1. It is forbidden for women in early pregnancy and before delivery.
2. Patients with arrhythmia, recent myocardial infarction, hypertension and hyperthyroidism are prohibited .
Clenbuterol is taken orally in excess, and the symptoms disappear after administration of β-receptor antagonist, and it has mutual antagonism with β-receptor antagonist .
Rarely, there are mild heart palpitations, finger tremors, dizziness, etc., which can be relieved by itself during the course of medication. 
1. 20-40μg each time, 3 times a day.
2. Sublingual administration: 60~120μg each time, first sublingual administration. After the asthma is relieved, take the remaining part with warm water.
3. Aerosol inhalation: 10-20μg each time, 3 to 4 times a day.
4. Rectal administration: 2 times a day (or 1 time before going to bed), 60μg each time. 
Interactions with other drugs
(Not yet clear) 
According to domestic reports, clinically used for inhaled bronchial asthma without infection, the effective rate of immediate relief of asthma is 83.5%, with an average effect of 10 minutes and a significant effect in 20 minutes, maintaining an average of more than 5-6 hours. The curative effect of aerosol inhalation is similar to that of oral administration, with faster onset and shorter duration. The effective rate of anal suppositories is 94.5%, and the clinical control and effective rate is 62%. According to another report, the lung function of 32 cases of acute childhood asthma was greatly improved after inhalation of clenbuterol. After 10 minutes of treatment, 25 cases of lung rales disappeared; 6 hours after treatment, only 2 cases of the whole group developed lungs. Rales. In another 264 cases of asthmatic bronchitis, the effective rate of Clenbuterol was 89.7%, and the clinical control and effective rate was 53%. Asthma patients take 30μg each time, which can significantly increase vital capacity per second (FEV1) and maximum expiratory flow rate (MEF), and reduce airway resistance. Its anti-asthmatic effect is comparable to that of hydroxybutyrol (5mg each time, 3 times a day). Compared to the latter, it is 165 times stronger than the latter. Clenbuterol can enhance the movement of cilia and promote the discharge of sputum, which helps to improve the efficacy of anti-asthmatic. 
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